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Cardiogenic shock is a life-threatening medical condition resulting from an inadequate circulation of blood due to primary failure of the ventricles of the heart to function effectively.〔Textbooks of Internal Medicine * (Harrison's Principles of Internal Medicine ) 16th Edition, The McGraw-Hill Companies, ISBN 0-07-140235-7 * (Cecil Textbook of Medicine ) by Lee Goldman, Dennis Ausiello, 22nd Edition (2003), W.B. Saunders Company, ISBN 0-7216-9652-X * (The Oxford Textbook of Medicine ) Edited by David A. Warrell, Timothy M. Cox and John D. Firth with Edward J. Benz, Fourth Edition (2003), Oxford University Press, ISBN 0-19-262922-0〕〔 (Shock: An Overview ) PDF by Michael L. Cheatham, MD, Ernest F.J. Block, MD, Howard G. Smith, MD, John T. Promes, MD, Surgical Critical Care Service, Department of Surgical Education, Orlando Regional Medical Center Orlando, Florida〕 As this is a type of circulatory shock, there is insufficient perfusion of tissue to meet the demands for oxygen and nutrients. Cardiogenic shock is a largely irreversible condition and as such is more often fatal than not. The condition involves increasingly more pervasive cell death from oxygen starvation (hypoxia) and nutrient starvation (e.g. low blood sugar). Because of this, it may lead to cardiac arrest (or circulatory arrest), which is an abrupt stopping of cardiac pump function.〔 Cardiogenic shock is defined by sustained low blood pressure with tissue hypoperfusion despite adequate left ventricular filling pressure. Signs of tissue hypoperfusion include oliguria (<30 mL/h), cool extremities, and altered level of consciousness. Treatment of cardiogenic shock depends on the cause. If due to a heart attack attempts to opening the arteries to the heart may help. An intra-aortic balloon pump or left ventricular assist device may improve matter until this can be done. Inotropes may help; however, it is unclear which is best. Norepinephrine may be better if the blood pressure is very low while dopamine or dobutamine may be more useful if only slightly low. ==Signs and symptoms== * Anxiety, restlessness, altered mental state due to decreased blood flow to the brain and subsequent hypoxia. * Low blood pressure due to decrease in cardiac output. * A rapid, weak, thready pulse due to decreased circulation combined with tachycardia. * Cool, clammy, and mottled skin (cutis marmorata) due to vasoconstriction and subsequent hypoperfusion of the skin. * Distended jugular veins due to increased jugular venous pressure. * Oliguria (low urine output) due to inadequate blood flow to the kidneys if the condition persists. * Rapid and deeper respirations (hyperventilation) due to sympathetic nervous system stimulation and acidosis. * Fatigue due to hyperventilation and hypoxia. * Absent pulse in fast and abnormal heart rhythms. * Pulmonary edema, involving fluid back-up in the lungs due to insufficient pumping of the heart. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「cardiogenic shock」の詳細全文を読む スポンサード リンク
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